Ronald B. Hirschl, M.D.
Arnold Coran Professor of Surgery
Head, Section of Pediatric Surgery

Practicing at:
C.S. Mott Children's Hospital

PEER-REVIEWED PUBLICATIONS

Publications (2001 to present)

  1. Younger JG, Sasaki N, Waite MD, Murray HN, Saleh EF, Ravage ZA, Hirschl RB, Ward PA, Till GO. Detrimental effects of complement activation in hemorrhagic shock. J Appl Physiol 90(2):441-6, 2001.
  2. Cassidy KJ, Bull JL, Glucksberg MR, Dawson CA, Haworth ST, Hirschl RB, Gavriely N, Grotberg JB: A rat lung model of instilled liquid transport in the pulmonary airways. J Appl Physiol 90. 1955-1967, 2001.
  3. Reickert CA, Pranikoff T, Overbeck MC, Kazerooni EA, Massey KD, DeAngelo LM, Cascade PN, Bartlett RH, Hirschl RB. The pulmonary and systemic distribution and elimination of perflubron from adult patients treated with partial liquid ventilation. Chest 119(2)515-522, 2001.
  4. The Congenital Diaphragmatic Hernia Study Group. Estimating disease severity of congenital diaphragmatic hernia in the first five minutes of life. J Ped Surg 36:141-145, 2001.
  5. Lewis DA, Colton D, Johnson KJ, Hirschl RB: Prevention of ventilator-induced lung injury with partial liquid ventilation. J Ped Surg 36(9):1333-1336, 2001.
  6. Fernandez R, Sarma V, Younkin E, Hirschl RB, Ward PA, Younger JG: Exposure to perflubron is associated with decreased Syk phosphorylation in human neutrophils. J Appl Physiol 91:1941-1947, 2001.
  7. Haft JW, Montoya JP, Alnajjar O, Posner SR, Bull, JL, Iannettoni MD, Bartlett RH, Hirschl RB. An artificial lung reduces pulmonary input impedance and improves right ventricular efficiency in acute pulmonary hypertension. J Thorac Cardiovasc Surg 122: 1094-1100, 2001.
  8. Fauza D, Hirschl RB, Wilson JM. Continuous intrapulmonary distention with perfluorocarbon accelerates Lung growth in infants with congenital diaphragmatic hernia: initial experience. J Ped Surg 36(8):1237-1240, 2001.
  9. Reickert CA, Rich PB, Crotti S, Mahler SA, Awad SS, Lynch WR, Johnson KJ, Hirschl RB. Partial liquid ventilation and positive end-expiratory pressure reduce ventilator-induced lung injury in an ovine model of acute respiratory failure. Crit Care Med 30 (1):182-189, 2002.
  10. Teitelbaum, DH, Lelli JL. Hirschl RB, Geiger JD, Arca MJ: Laparoscopy-assisted proctocolectomy for ulcerative colitis: A more rational approach. Pediatr Endosurgy & Innov Techniques 5(3):229-33 , 2001.
  11. Campbell BT, McLean K, Barnhart DC, Drongowski RA, Hirschl RB: A comparison between laparoscopic and open pyloromyotomy at a teaching hospital. J Pediatr Surg 37(7):1068-1071, 2002.
  12. Hirschl RB, Croce M, Gore D, Weidemann H, Davis K, Zwischenberger J, Bartlett RH for the Adult PLV Study Group. Prospective, Randomized Controlled Pilot Study Evaluating the Safety and Efficacy of Partial Liquid Ventilation in Adult Patients with the Acute Respiratory Distress Syndrome (ARDS). AJRCCM 165(6):781-787, 2002.
  13. Sawada S, Matsuda K, Younger JG, Johnson KJ, Bartlett RH, Hirschl RB. Effects of partial liquid ventilation during unilateral lung injury in dogs. Chest 121(2):556-576, 2002.
  14. Pranikoff T, Campbell BT, Travis J, Hirschl RB: Differences in outcome with subspecialty care: Pyloromyotomy in North Carolina. J Ped Surg 37(3):352-356, 2002.
  15. Haft JW, Griffith BP, Hirschl RB, Bartlett RH: Results of an artificial-lung survey to lung transplant program directors. The Journal of Heart and Lung Transplantation 21(4):467-473, 2002.
  16. Graziano K, Teitelbaum DH, Hirschl RB, Coran AG: Vaginal reconstruction for ambiguous genitalia and congenital absence of the vagina: A 27-year experience. J Ped Surg 37(7):955-60, 2002.
  17. Casetti A, Bartlett RH, Hirschl RB. Increasing inspiratory time exacerbates ventilator induced lung injury during high-pressure/high-volume mechanical ventilation. Crit Care Med 30(10):2295-2299, 2002.
  18. Foley DS, Pranikoff T, Younger JG, Swaniker F, Hemmila MR, Remenapp RA, Copenhaver W, Landis D, Hirschl RB, Bartlett RH. A review of 100 patients transported on extracorporeal life support. ASAIO 48(6):612-619, 2002.
  19. Hirschl RB, Yardeni D, Oldham K, Sherman N, Siplovich L, Gross E, Udassin R, Cohen Z, Nagar H, Geiger JD, Coran AG: Gastric transposition for esophageal replacement in children: Experience with 41 consecutive cases with special emphasis on esophageal atresia. Ann Surg 236(4):531-9, 2002.
  20. Hemmila MR, Foley DS, Casetti AV, Soldes OS, Hirschl RB, Bartlett RH. Perfusion induced hyperthermia for oncologic therapy with cardiac and cerebral protection. ASAIO 48(4):350-4, 2002.
  21. Hirschl RB: Support of respiratory failure in the pediatric surgical patient. Curr Opin Pediatr 14(4):459-69, 2002.
  22. Haft JW, Bull JL, Rose R, Kastra J, Grotberg JB, Bartlett RH, Hirschl RB: Design of an artificial lung compliance chamber for pulmonary replacement. ASAIO 49(1):35-40, 2003.
  23. Hirschl RB, Fox W, Glick P, Greenspan J, Smith K, Thompson A, Adzick S: A prospective, randomized pilot trial of perfluorocarbon-induced lung growth (PILG) in newborns with congenital diaphragmatic hernia (CDH). J Ped Surg 38(3):283-289, 2003.
  24. Campbell BT, Braun T, Schumacher R, Bartlett RH, Hirschl RB, : Impact of ECMO on neonatal mortality in Michigan (1980-1999). J Ped Surg 38(3):290-295, 2003.
  25. Ko AC, Hirsh E, Wong AC, Moore TM, Taylor AE, Hirschl RB, Younger JG: Segmental hemodynamics during partial liquid ventilation in isolated rat lungs. Resuscitation 57:85-91, 2003.
  26. Matsuda K, Sawada S, Bartlett RH, Hirschl RB: The effect of ventilatory parameters upon gas exchange and hemodynamics during total liquid ventilation in a rat model. Crit Care Med 37(7):2034-2040, 2003.
  27. Funakubo A, Taga I, McGillicuddy JW, Higami T, Fukui Y, Hirschl, RB, Bartlett RH: Flow vectoral analysis in an implantable lung. ASAIO (in press).
  28. Boules T, Hemmila M, Miskulin J, Annich G, Grams R, Hirschl RB, Bartlett RH: Extracorporeal life support as a treatment for septic shock. ASAIO (in press).
  29. Miskulin J, Annich G, Grams R, Boules T, Hirschl RB, Bartlett RH: Venous-arteriovenous cannulation for adult ECMO patient with cardiogenic shock. ASAIO (in press).
  30. Boules T, Kemppainen J, Miskulin J, McGillicuddy JW, Younger JG, Annich G, Funakuno A, Lambert M, Hirschl RB, Bartlett RH: Do induced secondary flows augment the clearance of protein-bound substances during albumin hemodiafiltration? ASAIO (in press).
  31. Haft JW, Alnajjar O, Bull JL, Lambert MB, Li P, Chambers S, Bartlett RH, Hirschl RB: Effect of compliance on the right ventricle during perfusion of an artificial lung. Surgery (in press).
  32. Graziano K, Teitelbaum DH, McLean K, Hirschl RB, Coran AG, Geiger JD: Recurrence after laparoscopic and open nissen fundoplication: A comparison of the mechanisms of failure. Surgical Endoscopy (in press).
  33. Wildhaber, B, Coran, AG, Drongowski, RA, Hirschl, RB, Geiger, JD, Lelli, JL, Teitelbaum, DH: The Kasai portoenterostomy for biliary atresia: A review of 27-year experience with 81 patients. J Ped Surg (In press).
  34. Geiger JD, Teitelbaum DH, Hirschl RB, Coran AG: A new operative technique for restorative proctocolectomy: The endorectal pull-through combined with a double-stapled ileo-anal anastomosis. Surgery (in press).
  35. Meinhardt JP, Ashton BA, Annich GM, Quintel M, Hirschl RB: The dependency of expiratory airway collapse on pump system and flow rate in liquid ventilated rabbits. Eur J Med Res (in press).
  36. Baba Y, Brant D, Sukhjinder S, Grotberg J, Bartlett RH, Hirschl RB. Assessment of the development of choked flow during total liquid ventilation. Critical Care Medicine (in press).
  37. Meinhardt JP, Ashton BA, Annich GM, Hirschl RB. The dependency of expiratory airway closure on pump system and flow rate in total liquid ventilated rabbits. European Journal of Critical Care Medicine (in press).
  38. Neville HL, Jaksic T, Wilson JM, Lally PA, Hardin W, Hirschl RB, Lally KP: Bilateral congenital diaphragmatic hernia (CDH): A Report of the Congenital Diaphragmatic Hernia Study Group. J Ped Surg (in press).
  39. Neville HL, Jaksic T, Wilson JM, Lally PA, Hardin WD Jr., Hirschl RB, Langham, MR Jr., Lally KP: Fryns syndrome in children with congenital diaphragmatic hernia (CDH): A Report of the Congenital Diaphragmatic Hernia Study Group. J Ped Surg (in press)
  40. Sawada S, Matsuda K, Johnson KJ, Younger J, Bartlett RH, Hirschl RB. Total liquid ventilation reduces neutrophil accumulation in the setting of acute lung injury in rats. J Crit Care (in press).

Chapters (2000 to present)

  1. Hirschl RB: Mechanical Ventilation in Pediatric Surgical Disease. Pediatric Surgery. Third Edition, WB Saunders Company, pp. 72-94, 2000.
  2. Foley DS, Hirschl RB: Liquid Ventilation for Neonatal Respiratory Failure. In Donn SM, Sinha SK, Manual of Neonatal Respiratory Care. Futura Publishing Corp., New York, pp. 447-452, 2000.
  3. Foley DS, Hirschl RB: Liquid Ventilation in the Setting of Severe Respiratory Failure. In Zwischenberger JB, Steinhorn RH, Bartlett RH (eds), ECMO: Extracorporeal Cardiopulmonary Support in Critical Care, Second Edition, published by Extracorporeal Life Support Organization (ELSO), pp. 709-727, 2000.
  4. Hirschl RB: Devices in ECLS. In Zwischenberger JB, Steinhorn RH, Bartlett RH (eds) ECMO: Extracorporeal Cardiopulmonary Support in Critical Care, Second Edition, published by Extracorporeal Life Support Organization (ELSO), pp. 199-232, 2000.
  5. Hirschl RB: Regulatory Issues Related to ECLS. In Zwischenberger JB, Steinhorn RH, Bartlett RH (eds), ECMO: Extracorporeal Cardiopulmonary Support in Critical Care, Second Edition, published by Extracorporeal Life Support Organization (ELSO), pp. 701-708, 2000.
  6. Foley DS, Hirschl RB: Liquid Ventilation. In MacIntyre J, Branson R (eds) Mechanical Ventilation. W. B. Saunders Co., Philadelphia, pp.433-453, 2001.
  7. Foley DS, Hirschl RB: Liquid Ventilation for Adult Respiratory Failure. In Dietch E, Vincent JL, Windsor ACJ (eds), Sepsis and multiple Organ Dysfunction: A multidisciplinary approach, W.B. Saunders Co., London, England, pp. 381-389, 2002.
  8. Hirschl RB: Surgical Emergencies. In Donn SM (ed.): The Michigan Manual of Neonatal Intensive Care. 3rd Edition. Philadelphia, PA, Hanley & Belfus, 2003.
  9. Soldes O, Hirschl RB: Congenital Diaphragmatic Hernia. In Donn SM (ed.): The Michigan Manual of Neonatal Intensive Care. 3rd Edition. Philadelphia, PA, Hanley & Belfus, 2003.
  10. Hirschl RB, Coran AG: Prenatal and Fetal Surgery, Essentials of Pediatric Surgery, Edited by O'Neill JA, Grosfeld JL, Coran AG, and Fonkalsrud EW, Mosby and Co., Philadelphia, 2003.
  11. Hirschl RB, Coran AG: Respiratory Considerations and Tracheal Access, Essentials of Pediatric Surgery, Edited by O'Neill JA, Grosfeld JL, Coran AG, and Fonkalsrud EW, Mosby and Co., Philadelphia, 2003.
  12. Hirschl RB, Coran AG: Cardiovascular Considerations and Vascular Access, Essentials of Pediatric Surgery, Edited by O'Neill JA, Grosfeld JL, Coran AG, and Fonkalsrud EW, Mosby and Co., Philadelphia, 2003.
  13. Hirschl RB, Coran AG: Special Considerations in Pediatric Anesthesia, Essentials of Pediatric Surgery, Edited by O'Neill JA, Grosfeld JL, Coran AG, and Fonkalsrud EW, Mosby and Co., Philadelphia, 2003.
  14. Hirschl RB, Coran AG: Gastrointestinal Bleeding, Essentials of Pediatric Surgery, Edited by O'Neill JA, Grosfeld JL, Coran AG, and Fonkalsrud EW, Mosby and Co., Philadelphia, 2003.
  15. Hirschl RB, Coran AG: Appendicitis, Essentials of Pediatric Surgery, Edited by O'Neill JA, Grosfeld JL, Coran AG, and Fonkalsrud EW, Mosby and Co., Philadelphia, 2003.
  16. Hirschl RB, Coran AG: Anorectal Disorders and Imperforate Anus, Essentials of Pediatric Surgery, Edited by O'Neill JA, Grosfeld JL, Coran AG, and Fonkalsrud EW, Mosby and Co., Philadelphia, 2003.
  17. Hirschl RB, Coran AG: Cardiovascular Disorders, Essentials of Pediatric Surgery, Edited by O'Neill JA, Grosfeld JL, Coran AG, and Fonkalsrud EW, Mosby and Co., Philadelphia, 2003.