David E. Misek, Ph.D. is a Research Assistant Professor in the Section of General Surgery, at the University of Michigan Health Systems in Ann Arbor, Michigan. Dr. Misek received his Bachelor of Science degree from Colorado State University in Ft. Collins, Colorado in 1979. He continued on for his Ph.D. in Pathology which he received in 1986, from the State University of New York, Downstate Medical Center, in Brooklyn, New York. Dr. Misek did postdoctoral training in the Department of Genetics and Development at Columbia University College of Physicians and Surgeon's from March 1986 to July of 1989. He did additional postdoctoral work at Rockefeller University from 1989 to June of 1990, in the Department of Molecular Oncology with Dr. Alan Saltiel. He continued his work with Dr. Saltiel at the University of Michigan Medical School in the Department of Physiology and Parke-Davis Pharmaceutical Research, Department of Signal Transduction, from July 1990 thru 1993.

In February of 1994, Dr. Misek joined the faculty at the University of Michigan Medical School as an Assistant Research Scientist in Internal Medicine Endocrinology and Metabolism. He was appointed Senior Research Associate in Pediatrics and Communicable Diseases (Hematology/Oncology), in March of 1997. In July of 2006, Dr. Misek joined the faculty in the Section of General Surgery, Department of Surgery, in the University of Michigan Health Systems, as a Research Assistant Professor.

Dr. Misek's research interests are in cancer-related proteomic and genomic alterations in the cell. He has been a leader in the development of multidimensional liquid-based separation technologies for the analysis of cancer and patient serum, in the application of 2-D PAGE to the study of cancer and to the study of the humoral response to cancer. Further, he has been involved in the development and application of both protein and cDNA microarray technologies to the study of cancer.