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Current Pediatric Cardiovascular Research

The pediatric surgeons at the University of Michigan are at the cutting edge of new technology and new procedures while being involved with numerous research projects aimed at increasingly better patient outcomes. Families may be asked on behalf of their child to be a part of certain research projects while their child is being cared for. A few of the latest research projects are listed below.

  • Dr. Bove is part of an on-going, multicenter study that tracks data throughout the world on pulmonary atresia, interrupted aortic arch, aortic atresia, aortic stenosis, tricuspid atresia and transposition of the great arteries. This is done by the Congenital Heart Surgeon's Society Studies.
  • Dr. Ohye along with one the pediatric cardiologist, Dr. Goldberg, is involved in a study looking at the Medtronic contegra pulmonary valved conduit. This study is to evaluate the effectiveness and safety of this conduit as a replacement for diseased, malformed or absent pulmonary valves.
  • Dr. Ohye is involved in a study of unbalanced atrioventricular septal defects patients. This is a retrospective review of all patients undergoing surgical repair from 1993-2003. The study looks at the issue of a one ventricle repair versus a two ventricle repair and how that was determined.
  • Dr. Bove is heading up a study on the Ross procedure in the pediatric age group, looking at long term outcomes. This study is tracking patients from 1991-2003. The purpose is to evaluate the long-term outcomes with regards to re-operation.
  • Dr. Ohye has just begun working on a study looking at HLA antibody development in infants receiving cyropreserved pulmonary allografts.
  • Dr. Ohye is also looking at a comparative, masked, randomized multicenter study to determine the safety and effectiveness of REPEL-CV for reducing post-operative adhesions following cardiovascular surgery. This study has been approved but not yet started.